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International Journal of Surgical Pathology
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Reviews

Pigmented Oral Squamous Cell Carcinoma: A Case Report and Brief Review of the Literature

Jurema Lisboa Castro, DDS, PhD

Department of Oral Pathology, Federal University of Pernambuco, Recife, Brazil

Claudia Cazal, DDS, PhD

Department of Oral Pathology, Federal University of Pernambuco, Recife, Brazil, claudiacazal{at}yahoo.com.br

Águida Cristina Gomes Henriques, DDS

Department of Oral Pathology, Federal University of Pernambuco, Recife, Brazil

Jair Carneiro Leão, DDS, PhD

Department of Oral Diagnosis Federal University of Pernambuco, Recife, Brazil

Marianne de Vasconcelos Carvalho, DDS

Department of Oral Diagnosis Federal University of Pernambuco, Recife, Brazil

Hilda Texeira de Carvalho Dourado, DDS

Department of Oral Diagnosis Federal University of Pernambuco, Recife, Brazil

Alessandra A. Tavares Carvalho, DDS, PhD

Department of Oral Diagnosis, Federal University of Pernambuco, Recife, Brazil

Melanin impregnation in squamous cell carcinoma (SCC) is an uncommon histological finding. Rare nonmelanocytic entities were previously described as having melanocyte colonization. A 57-year-old Brazilian woman was referred with a pigmented lesion in the lower lip and alveolar ridge with a prior clinical diagnosis of melanoma. The incisional biopsy of the tumor revealed an SCC with strong colonization of melanocytes in the stroma. The authors report a case of an unusual SCC variant and a brief review of the literature.

Key Words: squamous cell carcinoma • melanocyte colonization • melanin • oral mucosa

This version was published on April 1, 2009

International Journal of Surgical Pathology, Vol. 17, No. 2, 153-157 (2009)
DOI: 10.1177/1066896908315747
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