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International Journal of Surgical Pathology
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Reviews

Primary Carcinosarcoma of the Spleen: Case Report of a Rare Tumor and Review of The Literature

Kunal Kochar, MRCS

Department of Surgery, George Eliot Hospital, Nuneaton, West Midlands, United Kingdom, kocharkunal{at}hotmail.co.uk

Chandrasekar Vijayasekar, FRCS

Department of Surgery, George Eliot Hospital, Nuneaton, West Midlands, United Kingdom

Urmila Pandey, MRCPath

Department of Pathology, George Eliot Hospital, Nuneaton, West Midlands, United Kingdom

Ricky Bhogal, MRCS

Department of Surgery, George Eliot Hospital, Nuneaton, West Midlands, United Kingdom

Louise Brown, FRCPath

Department of Pathology, George Eliot Hospital, Nuneaton, West Midlands, United Kingdom

George Mathew, FRCS

Department of Surgery, George Eliot Hospital, Nuneaton, West Midlands, United Kingdom

Carcinosarcoma of extragenital organs is rare. In this article, a case of primary carcinosarcoma of the spleen, which presented as painful splenomegaly is reported. To the best of our knowledge, this is the second reported case of primary splenic carcinosarcoma in English literature. The pathogenesis of these tumors is incompletely understood. No specific treatment guidelines exist for these aggressive tumors, surgery being the mainstay of treatment. The prognosis remains poor regardless of the adjuvant therapy used.

Key Words: carcinosarcoma • spleen

This version was published on February 1, 2009

International Journal of Surgical Pathology, Vol. 17, No. 1, 72-77 (2009)
DOI: 10.1177/1066896908316070
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