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International Journal of Surgical Pathology
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Multicentric Basaloid Carcinoma of Lung Clinically Mimicking Metastatic Carcinoma: A Case Report

Sharathkumar Bhagavathi, MD

Department of Anatomic Pathology, William Beaumont Hospital, Royal Oak, Michigan, vmsharathkumar{at}yahoo.com

Chung-Ho Chang, MD

Department of Anatomic Pathology, William Beaumont Hospital, Royal Oak, Michigan

Basaloid carcinoma of lung is a highly aggressive form of non-small cell and non-neuroendocrine pulmonary carcinoma. It may exist in pure form or may admixed with other types of non-small cell lung carcinoma. A unique case of a multicentric basaloid carcinoma of lung is reported in this study. The patient was an 81-year-old male who was found to have 2 separate nodules of the left lung on computed tomography scan. He underwent wedge resection of both nodules. The morphology of the lesions was identical and consistent with basaloid carcinoma. Extensive workup to detect a possible extrapulmonary primary site was negative. Loss of heterozygosity studies performed on the 2 tumors were consistent with multicentric rather than metastatic nature.

Key Words: multicentric • basaloid carcinoma • LOH

This version was published on February 1, 2009

International Journal of Surgical Pathology, Vol. 17, No. 1, 68-71 (2009)
DOI: 10.1177/1066896908316900
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