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International Journal of Surgical Pathology
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What's this?

Cystic Struma Ovarii (With Macrocystic Change)

Sandra C. Piragua, MD

Department of Pathology, Baystate Medical Center, Tufts University School of Medicine, Springfield, Massachusetts

Christopher N. Otis, MD

Department of Pathology, Baystate Medical Center, Tufts University School of Medicine, Springfield, Massachusetts

Michel Prefontaine, MD

Department of Gynecology (Oncology), London Health Sciences Centre, Canada

Liron Pantanowitz, MD

Department of Pathology, Baystate Medical Center, Tufts University School of Medicine, Springfield, Massachusetts, Liron.pantanowitz{at}bhs.org

In this article, a case of cystic struma ovarii with macrocystic change is presented. Cysts derived from struma ovarii may mimic a mucinous or serous cystadenoma. A careful examination for any thyroid microfollicles within fibrous septa or areas of solid stroma is key. In problematic cases, immunohistochemical staining with thyroglobulin and thyroid transcription factor-1 may be required to establish the diagnosis.

Key Words: cyst • ovary • struma ovarii • thyroid

This version was published on October 1, 2008

International Journal of Surgical Pathology, Vol. 16, No. 4, 433-434 (2008)
DOI: 10.1177/1066896908315752
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