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International Journal of Surgical Pathology
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1066896908319674v1
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What's this?

Biotin-Rich Intranuclear Inclusions: Have You Checked Your Immunohistochemical Controls?

Rania Bakkar, MD

Department of Pathology and Laboratory Medicine, University of Louisville Hospital, Louisville, Kentucky

Grace Moore, MD

Department of Pathology and Laboratory Medicine, University of Louisville Hospital, Louisville, Kentucky

Alvin Martin, MD

Department of Pathology and Laboratory Medicine, University of Louisville Hospital, Louisville, Kentucky

Houda Alatassi, MD

Department of Pathology and Laboratory Medicine, University of Louisville Hospital, Louisville, Kentucky, haalat01{at}gwise.louisville.edu

Intranuclear biotin interacts with avidin-biotin-complex used for viral immunoperoxidase detection giving false-positive results.

Key Words: biotin rich • endometrium • avidin-biotin-complex method • intranuclear inclusions • herpetic endometritis

This version was published on October 1, 2008

International Journal of Surgical Pathology, Vol. 16, No. 4, 424-425 (2008)
DOI: 10.1177/1066896908319674
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